RECON will
test the hypothesis
that
patients who have
symptomatic,
unilateral carotid
artery occlusion and
stage II cerebral
hemodynamic failure
as measured by
increased oxygen
extraction fraction
(OEF) on positron
emission tomography
(PET) will have
better cognitive
function following
EC-IC bypass when
compared with an
identical group of
patients treated
with best medical
therapy alone. We
will test this
hypothesis by
conducting a
randomized
single-blinded
prospective trial on
260 enrolled COSS
patients randomized
equally to surgical
or non-surgical
treatment.
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